페이지 정보작성자 관리자 댓글 0건 조회 1,271회 작성일 16-11-02 11:11
Regulation of DC development and DC-mediated T-cell immunity via CISH.
Cytokine inducible SH2-containing protein (CISH) plays a crucial role in type 1 dendritic cell (DC) development as well as in the DC-mediated activation of cytotoxic T lymphocytes (CTLs). CISH expression at late DC developmental stages shuts down the proliferation of DC progenitors by negatively regulating signal transducer and activator of transcription 5 (STAT5) and facilitates the differentiation of DCs into potent stimulators of CTLs.
등록된 댓글이 없습니다.