Faculty

권재영 교수님(Jae Young Kwon)

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작성일 21-04-27 17:24

본문


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 권재영 (Kwon, Jae Young)

 직함

 교수,  Professor

 전공

 생물학, Molecular neurogenetics

 연구실

 신경유전학연구실, Neurogenetics lab

 전화

 031-299-4495

 사무실

 제2과학관 32257

 홈페이지

 https://sites.google.com/view/neurogenetics-skku/home 

 이메일

 jykwon@skku.edu

Research Background
Chemosensory Perception in Drosophila
 
All animals are born with a set of instincts, or innate behaviors, and our main questions are how complex behaviors are organized in the nervous system and how they are programmed during development. For this, the chemosensory system would be one of the most excellent models. Smell and taste are known to be important for sensing predators, selecting mates as well as finding food. We would like to trace the neuronal pathways that mediate a complex instinctive behavior such as feeding, from sensory input through to motor output. We are using the fruit fly as a model system to study chemosensation.
 

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Functional study of chemosensory system in Drosophila larva


We aim to identify molecular and cellular components required for chemosensation such as chemosensory receptors, chemosensory neurons, and the downstream signaling pathways, as well as elucidate the process starting from chemosensory perception and ending in a motor reaction. Drosophila melanogaster larvae are used as a simple model system to gain insight into these processes. Through these studies we aim to establish a molecular neurogenetic understanding of how external stimuli is perceived and processed in the peripheral and central nervous system.


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Dissecting the interaction between nutrient sensing and homeostasis 


The propose of this study is the identification of novel function of chemosensory receptors in Drosophila melanogaster. Specifically, we are interested in the role of chemoreceptors in homeostatic maintenance.



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 Selected Publications

• Sung HY, Jeong YT, Lim JY, Kim H, Oh SM, Hwang SW, Kwon JY*, Moon SJ*.  Heterogeneity in the Drosophila gustatory receptor complexes that detect aversive compounds.  Nat Commun. (2017) Nov 14;8, 1484

• Lee MJ, Sung HY, Jo H, Kim HW, Choi MS, Kwon JY*, Kang K*.  Ionotropic Receptor 76b Is Required for Gustatory Aversion to Excessive Na+ in Drosophila.  Mol Cells. (2017) Oct;40(10):787-795.

• Kim H, Jeong YT, Choi MS, Choi J, Moon SJ*, Kwon JY*.  Involvement of a Gr2a-Expressing Drosophila Pharyngeal Gustatory Receptor Neuron in Regulation of Aversion to High-Salt Foods.  Mol Cells. (2017) May 31;40(5):331-338.

• Lim CM, Kwon JY*, Cho WJ*.  Field-Effect Transistor Biosensor Platform Fused with Drosophila Odorant-Binding Proteins for Instant Ethanol Detection.  ACS Appl Mater Interfaces. (2017) Apr 26;9(16):14051-14057.

• van Giesen L, Neagu-Maier GL, Kwon JY*, Sprecher SG*.  A microfluidics-based method for measuring neuronal activity in Drosophila chemosensory neurons.  Nat Protoc. (2016) Dec;11(12):2389-2400.

• Choi J, van Giesen L, Choi MS, Kang K, Sprecher SG*, Kwon JY*.  A Pair of Pharyngeal Gustatory Receptor Neurons Regulates Caffeine-Dependent Ingestion in Drosophila Larvae.  Front Cell Neurosci. (2016) Jul 19;10:181.

• Chen J, Kim SM, Kwon JY.  A Systematic Analysis of Drosophila Regulatory Peptide Expression in Enteroendocrine Cells.  Mol Cells. (2016) Apr 30;39(4):358-66.

• Park JH, Chen J, Jang S, Ahn TJ, Kang K, Choi MS*, Kwon JY*.  A subset of enteroendocrine cells is activated by amino acids in the Drosophila midgut.  FEBS Lett. (2016) Feb;590(4):493-500.

• Kim H, Choi MS, Kang K, Kwon JY.  Behavioral Analysis of Bitter Taste Perception in Drosophila Larvae.  Chem Senses. (2016) Jan;41(1):85-94.

• Chen J, Choi MS, Mizoguchi A, Veenstra JA, Kang K, Kim YJ*, Kwon JY*.  Isoform-specific expression of the neuropeptide orcokinin in Drosophila melanogaster.  Peptides. (2015) 68:50-7.

• Park J-H, and Kwon JY.  Heterogeneous expression of Drosophila gustatory receptors in enteroendocrine cells.  PLoS One. (2011) e29022.

• Park J-H, and Kwon JY.  A systematic analysis of Drosophila gustatory receptor gene expression in abdominal neurons which project to the central nervous system.  Mol. Cells (2011) 32(4):375-81.

 

 Funding
• 2017 – 2020  Analysis of the differentiation and function of Drosophila enteroendocrine cells, National Research Foundation of Korea
• 2016 – 2019 Molecular and cellular basis of taste perception in Drosophila, National Research Foundation of Korea

 Education and experiences
• 2018 - Professor, Dept. of Biological Sciences, Sungkyunkwan University
• 2012 - 2018 Associate Professor, Dept. of Biological Sciences, Sungkyunkwan University
• 2008 - 2012 Assistant Professor, Dept. of Biological Sciences, Sungkyunkwan University
• 2003 - 2008 Postdoc, MCDB, Yale University (Mentor: John R. Carlson, Ph.D.)
• 2000 - 2003 Department of Biology, Yonsei University (Mentor: Junho Lee, Ph.D.)
Dissertation: “Genome-wide analysis of ethanol response genes in the nematode Caenorhabditis elegans”
• 1998 - 2000 M.S., Department of Biology, Yonsei University (Mentor: Junho Lee, Ph.D.) Master Thesis: “Caenorhabditis elegans 
mediator complexes 
are required for developmental-specific transcriptional activation”
• 1991 - 1998 B.A., Department of Biology, Yonsei University

 People

Current Members
  

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 성하연 (Sung, Ha Yeon) 박사
 
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  신경유전학연구실
  031-299-4502
  제2과학관 32256
  low724@hanmail.net
 
 

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 장수인 (Jang, Sooin)
 과정  
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  석박사통합과정
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  031-299-4502
  제2과학관 32256
  infinitec@naver.com
  
 

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 임승연 (Lim, Seung yeon)
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  제2과학관 32256
  limsy0913@naver.com
  
 

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 Wayessa Rahel Asefa
  과정  
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  제2과학관 32256
  Rahelasefawoyessa@gmail.com
  
 

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 유승윤 (Yu, Seungyun)
 과정  
 연구실

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  석박사통합과정
  신경유전학연구실
  031-299-4502
  제2과학관 32256
  yuseungyun@naver.com
  

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 최형준 (Choi, Hyungjun)

 과정

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 석박사통합과정

 신경유전학연구실

 031-299-4502

 제2과학관 32256

 sky369j@naver.com 

 
Former Member

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 박정호 (Park, Jeong-Ho) 박사


 이메일


 
  mageguildmaster@hotmail.com 


 

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 김해인 (Kim, Haein) 박사

이메일 

  
  evodevo923@gmail.com 

   
 

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 진제 (Chen, Ji) 박사 

 
 


 



 이메일 

  
  
  
  
  

 chenjifly2008@yeah.net 

   
   

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최재균 (Choi, Jaekyun) 박사

 
 

 



 이메일
  

  
  
  
  
  

 feelbox87@nate.com 

 
   

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송혜진 (Song, Hyejin) 석사

    

 
 

 


 이메일



  
  
  
  
  

 heyjin113@naver.com 



   

 


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